Recent Submissions

Now showing items 101-110 of 4921

  • Nutrigenetic and nutrigenomic aspects of nutraceuticals in metabolic syndrome prevention 

    Defence status: DEFENDED
    Kábelová, Adéla (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 11. 9. 2025
    Metabolic syndrome (MetS) is a complex disorder characterized by insulin resistance. Its increasing prevalence worldwide highlights the need for effective strategies beyond pharmacotherapy to manage this condition. Among ...
  • Clinical and neurophysiological markers in functional movement disorders 

    Defence status: DEFENDED
    Nováková, Lucia (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 8. 9. 2025
    Functional motor disorders (FMD), previously referred to as conversion, psychogenic, or dissociative motor disorders, represent a complex and heterogeneous group of conditions characterized by a wide spectrum of abnormal ...
  • Implementace metodiky ChildTalks+ zaměřené na podporu duševního zdraví dětí, jejichž rodiče trpí duševní poruchou. 

    Defence status: DEFENDED
    Farářová, Adéla (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 24. 6. 2025
    This dissertation focuses on families in which parents suffer from mental disorders and raise minor children. These children represent a particularly vulnerable group at higher risk of developing and progressing their own ...
  • Možnosti predikce některých těhotenských patologií 

    Defence status: DEFENDED
    Kníže, Michal (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 24. 9. 2025
    This dissertation focuses on pregnancy pathologies from genetic, clinical, and economic perspectives, aiming to improve the understanding of risk factors and optimize care for pregnant women throughout the entire course ...
  • Development of hydrophilic polymer conjugates and molecular probes as antibody mimetics for biomedical applications 

    Defence status: DEFENDED
    Whole item or its parts have restricted access until 05. 09. 2027
    Beranová, Jana (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 5. 9. 2025
    Recently developed synthetic polymer conjugates of N-(2-hydroxypropyl) methacrylamide (HPMA) in combination with low-molecular-weight ligands, called iBodies, alongside with small molecular probes, represent a promising ...
  • Terapie plicní hypertenze u pacientů s pokročilým srdečním selháním a sníženou ejekční frakcí levé komory 

    Defence status: DEFENDED
    Reichenbach, Adrian (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 25. 9. 2025
    Introduction: Combined pre- and post-capillary pulmonary hypertension (Cpc-PH) markedly worsens outcomes in advanced heart-failure patients with reduced ejection fraction (HFrEF). Experimental and clinical data suggest ...
  • Vývoj počtu a charakteristik klientů a poskytovaných služeb v aplikační místnosti v Brně 

    Defence status: DEFENDED
    Dospivová, Lenka (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 10. 9. 2025
    Background: A drug consumption room is a specialized harm reduction service that provides a hygienic and safe environment for drug use under the supervision of trained professionals. The first injecting room in the Czech ...
  • Virtualizace ve stomatologii 

    Defence status: DEFENDED
    Hyšpler, Pavel (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 19. 5. 2025
    Fully digital workflows are beginning to dominate dental practices. The precision and accuracy of some intraoral scanners are not only sufficient but significantly surpass traditional impression techniques using plaster ...
  • Patofyziologie a diferenciální diagnostika třesu 

    Defence status: DEFENDED
    Hollý, Petr (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 24. 3. 2025
    1 Abstract The pathophysiology of tremor is diverse and, in some cases, not fully elucidated. In this thesis, we focus mainly on head tremor, which is a common symptom of essential tremor (ET), and cervical dystonia (CD). ...
  • Porucha chování v REM spánku 

    Defence status: DEFENDED
    Peřinová, Pavla (Univerzita Karlova, 1. lékařská fakulta, 2025)
    Date of defense: 24. 3. 2025
    REM SLEEP BEHAVIOR DISORDER Abstract The dissertation focuses on REM sleep behavior disorder (RBD), a disease characterized by motor and vocal manifestations resulting from disrupted muscle atonia, which is otherwise ...

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