Kvalifikační práce
Procházet dle
Poslední příspěvky
Zobrazují se záznamy 161-170 z 4989
-
Vrozené vady centrálního nervového systému v České republice
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2026)Datum obhajoby: 27. 1. 2026Introduction: Congenital developmental defects are defined as deviations from normal prenatal development of an individual that exceed the typical variability within the given population and are (at least to some extent) ... -
CRISPR/Cas9: as a new tool for study of oncogenic microRNA network in chronic lymphocytic leukemia
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 11. 9. 2025(EN) Background: Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults in the Western World and the average age at diagnosis is approximately 72 years old. CLL is a slow developing lymphoproliferative ... -
Možnosti predikce některých těhotenských patologií
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 24. 9. 2025This dissertation focuses on pregnancy pathologies from genetic, clinical, and economic perspectives, aiming to improve the understanding of risk factors and optimize care for pregnant women throughout the entire course ... -
The roles of ORMDL proteins in immunity and cellular metabolism
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 9. 6. 2025(EN) ORM-like (ORMDL) proteins are a family of highly homologous, evolutionarily conserved, transmembrane proteins localised to the endoplasmic reticulum (ER). Mammals express three ORMDL proteins, ORMDL1, ORMDL2 and ORMDL3, ... -
Correlation of quantitative imaging parameters with particular neurodegenerative phenotypes
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 8. 9. 2025Neurodegenerative disorders represent a significant public health challenge due to their high prevalence and substantial impact on quality of life. Biomarkers, including neuroimaging, are essential in their research. is ... -
Konzumace alkoholu a jiných návykových látek mladistvými v ČR, srovnání se světem
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 9. 9. 2025The diploma thesis comprehensively deals with the topic of alcohol and other addictive substances consumption among adolescents in the Czech Republic and makes a detailed international comparison. The main goal is a thorough ... -
Nutrigenetic and nutrigenomic aspects of nutraceuticals in metabolic syndrome prevention
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 11. 9. 2025Metabolic syndrome (MetS) is a complex disorder characterized by insulin resistance. Its increasing prevalence worldwide highlights the need for effective strategies beyond pharmacotherapy to manage this condition. Among ... -
Automatic detection of problematic situations from long-term monitored parameters in patients with type 1 diabetes
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2026)Datum obhajoby: 25. 3. 2026Type 1 diabetes requires continuous decision-making made by patients in everyday life, where even small mistakes in the treatment can lead to significant glycemic excursions. Despite advances in diabetes technologies, many ... -
Markery progrese aterosklerózy v definovaných populacích
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 16. 9. 2025(EN) Cardiovascular disease (CVD), especially atherosclerotic CVD (ASCVD), remains the leading cause of morbidity and mortality not only in the Czech Republic but also globally. ASCVD are defined by a number of non-/modifiable ... -
Možnosti predikce fyzikálních, laboratorních i klinických parametrů v počátku gestace a vyhodnocení jejich validity
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2025)Datum obhajoby: 16. 9. 2025The topic of this thesis is to search for new markers useful in the diagnosis of pre-eclampsia (PRE) and to verify their applicability on a broader laboratory scale in order to find a suitable diagnostic parameter for ...
