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Diabetes mellitus a přidružená onemocnění
Výsledek obhajoby: NEOBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2021)Datum obhajoby: 22. 6. 2021Diabetes mellitus is a non-communicable disease of mass occurrence. Diabetes itself is often associated with other diseases, such as diseases of the nervous or vascular system. This thesis deals with diabetes and these ... -
Studium mechanizmů vzniku a rozvoje perinatální hypoxie
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 22. 9. 2022Perinatal asphyxia is a condition resulting from hypoxic-ischemic injury in utero or during birth and causing perinatal morbidity and mortality. Up until now, numerous models of neonatal hypoxia-ischemia were created and ... -
Aplikovaná farmakokinetika v preklinickém výzkumu
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 27. 9. 2022Title: Applied pharmacokinetics in preclinical research Author: Mgr. Jana Královičová Abstract: This thesis addresses the topic of development and practical utilization of rat models in preclinical pharmacokinetic studies. ... -
Patofyziologie nitrokomorové propagace elektrického vzruchu a její vztah k srdeční resynchronizační léčbě
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 20. 10. 2022The QRS complex shortening by cardiac resynchronization therapy (CRT) has been associated with improved outcomes. We hypothesized that (1) the absence of QRS duration (QRSd) prolongation by right ventricular septal pacing ... -
Neuroprotective effects of novel anorexigenic analogs of prolactin-releasing peptide (PrRP) in models of neurodegeneration in vitro and in vivo
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 20. 10. 2022Alzheimer's disease (AD) is a progressive brain disorder characterized by extracellular beta amyloid (Aβ) plaques, intracellular neurofibrillary tangles formed by hyperphosphorylated Tau protein and neuroinflammation. Since ... -
Prognostic awareness in advanced cancer patients
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 25. 10. 2022Being aware of the severity of their medical condition is a key precondition for patients with advanced disease to be involved in advance care planning. This thesis aims to describe the phenomenon of prognostic awareness ... -
Role ergoterapie u osob s Duchennovou muskulární dystrofií
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 15. 9. 2022Author of bachelor thesis: Adéla Janatová Thesis supervisor: Bc. Zuzana Rodová, M.Sc. Title of bachelor thesis: The Role of Occupational Therapy in Duchenne Muscular Dystrophy Abstract of bachelor thesis: Duchenne Muscular ... -
The role of ghrelin signalling in the neurobiological mechanisms of rewarding effects of cannabinoids and opioids
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 21. 9. 2022Background: Ghrelin, an orexigenic appetite stimulating peptide, in addition to promoting energy balance, contributes to the rewarding effects associated with overeating. It also seems to play an important role in the ... -
Systém ergodiagnostických center v České republice a jeho fungování v procesu ergodiagnostiky z pohledu ergoterapeuta
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 16. 9. 2022Title: System of Prevocational Assessment Centers in the Czech Republic and his functioning in the process of Prevocational Assessment from the perspective of the Occupational therapist Abstract: Prevocational assessment ... -
Fenotyp melanocytů za fyziologických a patologických podmínek
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, 1. lékařská fakulta, 2022)Datum obhajoby: 20. 9. 2022In addition to the dominant keratinocytes and fibroblasts, melanocytes are also indispensable representatives of skin cell populations. Melanocytes are pigment cells whose primary function is to produce the pigment melanin, ...
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