Now showing items 1-20 of 27905

    • Study of quantitative parameters of Norway spruce needle structure under the effect of elevated CO₂ concentration and different irradiance 

      Defence status: DEFENDED
      Kubínová, Zuzana (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 24. 9. 2019
      Zuzana Kubínová: Study of Quantitative Parameters of Norway Spruce Needle Structure under the Effect of Elevated CO2 Concentration and Different Irradiance, Doctoral Thesis, Prague 2019 Abstract Atmospheric concentration ...
    • Využití genetické variability pro účely konzervační biologie: příkladové studie populací v lidské péči a přírodě 

      Defence status: DEFENDED
      Opelka Somerová, Barbora (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 26. 4. 2022
      2 Abstract In this dissertation thesis, I focused mainly on the topic of endangered species conservation in three projects, which were realized in cooperation with Prague ZOO. The other two subprojects, which are part ...
    • Regulace penicilin vazebného proteinu Pbp2a u Streptococcus pneumoniae 

      Defence status: DEFENDED
      Kubeša, Bohumil (Univerzita Karlova, Přírodovědecká fakulta, 2021)
      Date of defense: 21. 9. 2021
      Regulation of penicillin-binding protein Pbp2a in Streptococcus pneumoniae Streptococcus pneumoniae is an extracellular human pathogen that encodes a unique eukaryotic-type Ser/Thr protein kinase StkP in its genome. This ...
    • Materiály pro výuku biochemie na gymnáziích - hladké a kosterní svalstvo 

      Defence status: DEFENDED
      Honomichl, Petr (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 13. 6. 2022
      Modern society gives humanity many guarantees and many benefits. Although one of the biggest problems nowadays is that most of us spend much time sitting at computers or TVs. Another problem is the excess of an unsuitable ...
    • Karyotypová evoluce švábů podčeledi Oxyhaloinae 

      Defence status: DEFENDED
      Jankásek, Marek (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 17. 9. 2019
      Cockroaches of Afrotropical subfamily Oxyhaloinae (Blattodea: Blaberidae) are widely known due to the popularity of Madagascar hissing cockroaches as pet species. It is thus surprising that evolutionary relationships and ...
    • Diversity of microalgae from extreme habitats: linking phylogeny and ecology 

      Defence status: DEFENDED
      Barcyte, Dovile (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 18. 9. 2019
      The diversity of microalgae from extreme habitats is far from being fully explored and understood. This is due, in part, to limited sampling efforts along with complex algal taxonomy and systematics. In particular, little ...
    • The role of ORMDL3 in the IgE receptor signaling 

      Defence status: DEFENDED
      Vávrová, Petra (Univerzita Karlova, Přírodovědecká fakulta, 2020)
      Date of defense: 17. 9. 2020
      ORMDL proteins are regulators of serine palmitoyltransferase (SPT) enzyme, which catalyzes the first step of sphingolipid biosynthesis. Human and murine ORMDL family consists of three members, ORMDL1, ORMDL2 and ORMDL3. ...
    • Hledání genetických a molekulárních příčin familiární formy SAA amyloidózy 

      Defence status: DEFENDED
      Kmochová, Tereza (Univerzita Karlova, Přírodovědecká fakulta, 2020)
      Date of defense: 17. 9. 2020
      This work documents the first case of idiopathic AA amyloidosis in humans caused by mutation in the promoter region of SAA1 gene. Knowledge of the mechanism of the disease may be an indication for targeted treatment in the ...
    • Karyotypová evoluce afrických linií sklípkanů čeledi Theraphosidae 

      Defence status: DEFENDED
      Košátko, Prokop (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 17. 9. 2019
      Karyotypes of mygalomorph spiders are not satisfactorily known. This thesis is focused on the basic cytogenetic analysis of selected species of African clades of theraphosid mygalomorphs. It includes four subfamilies: ...
    • Role stromálních mesenchymálních buněk exprimujících fibroblastový aktivační protein v mikroprostředí nádorů mozku 

      Defence status: DEFENDED
      Výmola, Petr (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 18. 9. 2019
      High-grade astrocytic tumours are aggressive primary brain malignancies, from which the most malignant and the most common is glioblastoma multiforme with median survival 15 months. Fibroblast activation protein (FAP) is ...
    • Strukturní analýza molekulárních krystalů 

      Defence status: DEFENDED
      Janíček, Jakub (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 17. 9. 2019
      Summary: Diploma thesis covers characterization of molecular crystals by X-ray structural analysis. N-carbamimidazoylisonikotinamid and 1-phenylguanidin were chosen, because their potential use in second harmony generation. ...
    • Evoluční dynamika NORů řádu štírků (Arachnida: Pseudoscorpiones) 

      Defence status: DEFENDED
      Šilhavá, Alena (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 17. 9. 2019
      From the karyological point of view, pseudoscorpions are still a little known organisms. Until now, karyotypes of only 61 species from eight families were described, while the distribution of the nucleolar organizers is ...
    • Interaction of plants and soil and other factors affecting plant invasiveness 

      Defence status: DEFENDED
      Aldorfová, Anna (Univerzita Karlova, Přírodovědecká fakulta, 2019)
      Date of defense: 17. 9. 2019
      Plant invasions represent a major ecological and socio-economical issue and understanding the drivers as well as consequences of plant invasions is thus one of the main goals of plant ecology. It is equally important to ...
    • Role ubikvitin ligázy Fbxo38 v myší spermatogenezi 

      Defence status: DEFENDED
      Zobalová, Eliška (Univerzita Karlova, Přírodovědecká fakulta, 2021)
      Date of defense: 14. 9. 2021
      Cullin-dependent ubiquitin ligases are responsible for the regulation of most cellular processes. Despite their mutated forms being the cause of many human diseases, their physiological roles are not sufficiently described. ...
    • Syntéza vícenásobně záporně nabitých kotev se sulfonátovými skupinami 

      Defence status: DEFENDED
      Tomanová, Adéla (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 31. 5. 2022
      The scope of the bachelor thesis is the synthesis of derivatives derived from the neopentyl skeleton, containing one detection or reactive group and one, two or three sulfonate groups. These compounds have applications for ...
    • Syntéza derivátů azafluoranthenu pomocí C-H aktivace/anelace. 

      Defence status: DEFENDED
      Hladík, Ondřej (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      The azafluoranthenes are a small group of natural substances, occuring in tropical vines from Menispermaceae family. They display promising medicinal effects (such as anti-HIV, cytotoxic activity) and other biological ...
    • Evolution of mixed cultures of the pathogenic yeasts Candida albicans and Candida guilliermondii 

      Defence status: DEFENDED
      Hirko, Dominik (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 9. 6. 2022
      The objective of this thesis was to investigate how cocultures of Candida albicans and Candida guilliermondii change overtime under control conditions and under the influence of fluconazole. These species are opportunistic ...
    • Analysis of volcanic tremor during the 2021 Fagradalsfjall eruption 

      Defence status: DEFENDED
      Sova, František (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 30. 5. 2022
      Volcanic tremors are low frequency seismic events, occurring prior to or during eruptions and are believed to be caused by the movement of magma. The study of those events can reveal subsurface processes during volcanic ...
    • Glykokalixareny a jejich afinita k lidským galektinům 

      Defence status: DEFENDED
      Bálková, Denisa (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 9. 6. 2022
      Calix[n]arenes are macrocyclic compounds synthesized by the oligomerisation of phenol and formaldehyde. They can have different numbers of phenol rings and can adopt various conformations. As they can be easily modified, ...
    • Identifikace změn expresního profilu genů účastnících se rezistence v experimentálním in vivo modelu ovariálního karcinomu 

      Defence status: DEFENDED
      Bryndová, Barbora (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 9. 6. 2022
      Ovarian carcinoma is one of the most serious gynecological malignancies in the world. High mortality of this cancer is mainly due to the development of multiple drug resistance to conventional treatments involving taxanes. ...

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