Přírodovědecká fakulta
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GEOBIBLINE - plné texty [10555]
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Habilitační práce [73]
Habilitations -
Kvalifikační práce [19055]
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Kvalifikační práce obhajované před rokem 2006 [0]
Theses defended before year 2006
Poslední příspěvky
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Detecting biomarkers of extremophiles in Martian analogues
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2023)Datum obhajoby: 20. 3. 2023The main focus of this thesis is on the examination of endolithic microorganisms within gypsum from Sicily. This region is of particular interest because gypsum outcrops are common and accessible there, but the environment ... -
Reactive modifications of RNA for bioconjugations with proteins and new enzymatic methods for the synthesis of base-modified RNA
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 23. 2. 2024This doctoral thesis focuses on the enzymatic synthesis of base-modified RNA probes with diverse functional groups, including reactive cross-linking, hydrophobic and fluorescent moieties, or affinity tags. The construction ... -
Emoce a estetické preference vyvolané zvířaty v kontextu ochrany přírody
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 20. 2. 2024People have always seen animals as an important part of their lives. As a result of human activity and other factors, an increasing number of species are becoming endangered. Recently, nature conservation has become ... -
Calcareous nannofossils assemblages for provenance analysis of European paintings: From the sample preparation to the assemblage comparison
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2023)Datum obhajoby: 15. 3. 2023This PhD thesis is a commentary of four studies published and a fifth study submitted in peer reviewed and impacted scientific journals. Three studies are methodological work for the preparation of painted micro-samples ... -
Subjektivní a psychofyziologické parametry emocí, které vzbuzují různé skupiny zvířat
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 28. 2. 2024SUBJEKTIVNÍ A PSYCHOFYZIOLOGICKÉ PARAMETRY EMOCÍ, KTERÉ VZBUZUJÍ RŮZNÉ SKUPINY ZVÍŘAT Mgr. Šárka Peterková Abstract The central theme of this dissertation is human evaluation of animals from the perspective of subjectively ... -
Species traits of soil fauna and ecosystem functions during recovery after major disturbances
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 21. 2. 2024Growing evidence indicates that interactions between above and belowground communities are essential for healthy and functioning ecosystems. This, however, has exposed a disproportionate knowledge gap in soil communities, ... -
Ambient noise investigation of rock structures in Bohemian Paradise
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 4. 3. 2024We carry out non-invasive ambient noise investigation of rock structures in Bohemian Paradise (Bohemian Cretaceous Basin, Czech Republic). The study is focused on two key topics: 1) An in-situ elastic moduli estimate of ... -
Structural studies of selected protein complexes involved in signal transduction
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 19. 2. 2024Protein-protein interactions are critical for most physiological and pathophysiological processes. Detailed characterization of these interactions is therefore essential not only to understand the nature of these events, ... -
Structural studies of an abasic site DNA damage repair and DNA interstrand cross-link formation
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 19. 2. 2024DNA damage refers to any alteration or modification in the DNA structure that deviates from its natural state. Abasic site (Ap site) is one of the most common DNA lesions resulting from spontaneous depurination/depyrimidination ... -
Synthesis, processing and properties of high-temperature ceramic oxygen conductors
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 1. 3. 2024Ceramic oxygen conductors are important materials used as solid electrolytes in solid oxide fuel cells and oxygen sensors. Among the many electrolyte materials, cerium dioxide is attracting a lot of attention. This is ... -
Biofyzikální charakterizace inhibice koronavirové nsp14 malými molekulami
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 14. 2. 2024RNA virus SARS-CoV-2 caused worldwide pandemic of severe disease COVID-19 which lasted more than a year. Repair mechanisms of this virus during replication process significantly reduce efficiency of nucleotide analog drugs, ... -
Development of pharmacophore-guided molecular docking protocol for design of SARS-CoV-2 main protease inhibitors
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 14. 2. 2024Covid-19 is a highly contagious potentially life-threatening disease caused by the SARS-CoV-2 coronavirus. The virus is responsible for a global pandemic and has claimed over 6 million human lives between years 2020 and ... -
Aktivace protinádorové imunitní odpovědi s pomocí bispecifických fúzních proteinů
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 14. 2. 2024Natural killer (NK) cells are lymphocytes of the innate immune system that recognize and eliminate transformed and potentially harmful cells in a mechanism termed immunosurveillance. Malignant cells strive to escape ... -
Nové molekulární materiály pro optické aplikace - syntéza a studium solí 5-aminotetrazolu
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 14. 2. 2024Title: Novel Molecular Materials for Optics - Synthesis and Characterization of 5-aminotetrazole Salts Author: Stanislav Pospíöil Department: Department of Inorganic Chemistry Supervisor: Mgr. Martin Zábransk˝, Ph.D., ... -
Vliv znečištěného ovzduší na markery oxidačního poškození u novorozenců
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2020)Datum obhajoby: 3. 9. 2020In everyday life, humans are exposed to toxic substances of anthropogenic origin. These substances can also be found in the ambient air and their impact poses a long-term risk for human health. Respirable particulate matter ... -
Synthesis of tricyclic hydrocarbon derivatives
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 7. 2. 2024This bachelor thesis deals with the preparation of enantiopure Binol-derived phosphoric acids with different substituents at the 3,3'-position, which are typically used as Brønsted acids in enantioselective non-covalent ... -
Využití N-hydroxysukcinimidyl-formiátu jako zdroje CO v tandemových reakcích
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 7. 2. 2024This bachelor thesis deals with the use of N-hydroxysuccinimidyl formate as a source of CO in tandem reactions. The prepared starting materials were used in a tandem reaction involving cyclic carbopalladation, carbonylation ... -
Role of transcription factors MEIS in the origin and development of the neural crest
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 16. 2. 2024Unique to the vertebrate embryo, neural crest cells represent a multipotent cell population that migrates throughout the body and gives rise to a multitude of different types of cells and tissues. Cranial neural crest cells ... -
Changes of gut microbiome in patients with inflammatory bowel diseases
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 5. 2. 2024(EN) Microbes have coevolved with humans forming symbiotic communities that constantly challenge the immune system and, when imbalanced, could lead to diseases like inflammatory bowel disease (IBD). Patients with IBD suffer ... -
Generování těkavých chelátů zinku z vodné matrice
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2024)Datum obhajoby: 5. 2. 2024The topic of this work was optimization of the conditions for the generation of volatile zinc chelates. The aim was to develop an alternative method for generating volatile Zn speciates to its reduction by sodium ...