Recent Submissions

  • Analogues of IGF-1 for the study of interactions of the hormone with the receptors for IGF-1 and insulin 

    Macháčková, Kateřina (Univerzita Karlova, Přírodovědecká fakulta, 2019)
    Date of defense: 24. 4. 2019
    Insulin/IGF system is a complex network of three similar hormones (insulin, IGF-1 and IGF-2) and their three similar receptors (IR-A, IR-B and IGF-1R,), which play important roles in maintaining basal energy homeostasis ...
  • Chromatographic characterization of polyaniline-coated stationary phases 

    Taraba, Lukáš (Univerzita Karlova, Přírodovědecká fakulta, 2019)
    Date of defense: 17. 4. 2019
    (EN) This dissertation thesis is focused on physicochemical and chromatographic characterization of polyaniline-coated stationary phases. In the first part, surfaces of bare silica and octadecyl silica sorbents were modified ...
  • Azidoperfluoroalkanes: Synthesis and Application 

    Blastik, Zsófia Eszter (Univerzita Karlova, Přírodovědecká fakulta, 2019)
    Date of defense: 16. 4. 2019
    The incorporation of the trifluoromethyl and perfluoroalkyl motifs into organic compounds has been a hot topic in synthetic organofluorine chemistry. There is a plethora of methods for the introduction of the CF3 moiety ...
  • Příprava enantiomerně čistých cyklických sloučenin za využití organokatalýzy 

    Remeš, Marek (Univerzita Karlova, Přírodovědecká fakulta, 2015)
    Date of defense: 20. 3. 2015
    Since 2000 the organocatalytic synthesis has developed massively in a third pillar of asymmetric synthesis standing next to catalysis with metal complexes and enzymatic catalysis. Organocatalysts, due to their various ...
  • Využití sloučenin hypervalentního jodu a MBH karbonátů v organokatalýze 

    Kamlar, Martin (Univerzita Karlova, Přírodovědecká fakulta, 2015)
    Date of defense: 11. 9. 2015
    Beside transition-metal and enzymatic catalysis plays organocatalysis an important role in asymmetric organic sythesis. In the field of organocatalysis are amines group of compounds commonly used as organocatalysts. This ...
  • Nucleation of Sulphuric Acid and Water - Laboratory and Atmospheric Observations 

    Škrabalová, Lenka (Univerzita Karlova, Přírodovědecká fakulta, 2016)
    Date of defense: 26. 4. 2016
    1 ABSTRACT: This study is dedicated to the study of nucleation of sulphuric acid and water, which presents the key process associated with secondary aerosol formation via gas to particle conversion. We investigated the ...
  • Human-driven and natural vegetation changes of the last glacial and early Holocene 

    Kuneš, Petr (Univerzita Karlova, Přírodovědecká fakulta, 2008)
    Date of defense: 16. 5. 2008
    Conclusions The main conclusions, specific to each research topic, have been mentioned in appropriate chapter. To summarize, the thesis brings new original data and reinterprets existing pollen assemblages of the last ...
  • Mechanismy reparace DNA v mechu Physcomitrella patens 

    Holá, Marcela (Univerzita Karlova, Přírodovědecká fakulta, 2015)
    Date of defense: 16. 12. 2015
    Over the course of an organism's life, its genome is exposed to endogenous and exogenous chemical, physical and biological agents - genotoxins. These genotoxins alter its basic structural components - sugar residues, ...
  • Synthesis, characterization and catalytic application of novel zeolites 

    Eliášová, Pavla (Univerzita Karlova, Přírodovědecká fakulta, 2014)
    Date of defense: 25. 6. 2014
    The PhD thesis concerns the synthesis of novel zeolite materials, investigation of their properties and their possible use in catalytic application. The work was focused on the two- dimensional zeolites. The thesis was ...
  • The physiological and proteomic characterisation of winter oilseed rape upon abiotic stress 

    Urban, Milan (Univerzita Karlova, Přírodovědecká fakulta, 2017)
    Date of defense: 30. 5. 2017
    - Ph.D. thesis - Milan Urban, 2017 In some years, the agricultural production of oilseed rape, an important crop in the Czech Republic, is - besides biotic stress - facing the problem of damage caused by frost or drought. ...
  • Secondary metabolites, allelopathy and their significance in the invasion of Heracleum mantegazzianum 

    Jandová, Kateřina (Univerzita Karlova, Přírodovědecká fakulta, 2014)
    Date of defense: 26. 11. 2014
    One theory concerning the invasiveness of exotic plants suggests that they exude allelopathic compounds that are novel in areas being invaded. Here, I tested for allelopathic effects of root exudates of the invasive plant ...
  • Demonstrace jako prostředek názornosti v chemickém vzdělávání 

    Hájková, Zdeňka (Univerzita Karlova, Přírodovědecká fakulta, 2014)
    Date of defense: 18. 9. 2014
    Demonstrations are considered an important illustrative tool in chemistry education. Quite often teachers use demonstrations of experiments and multimedia demonstrations. Besides, "non-experimental" demonstrations might ...
  • Modeling of mass transport causal conditions 

    Bernsteinová, Jana (Univerzita Karlova, Přírodovědecká fakulta, 2015)
    Date of defense: 18. 9. 2015
    The evidence of a flood wave passing through a catchment remains visible even for a long time after it occurs. The morphological update in the channel and floodplains, together with the processes related to the mass transport ...
  • Preparation and characterization of new materials for metathesis and adsorption 

    Pastva, Jakub (Univerzita Karlova, Přírodovědecká fakulta, 2017)
    Date of defense: 30. 3. 2017
    The main objective of this work was to evidence versatile applications of ordered siliceous mesoporous materials, especially in adsorption and catalysis. For these reasons four mesoporous molecular sieves (SBA-15, SBA-16, ...
  • Solvent effects on ion pairing and photoionization in water 

    Pluhařová, Eva (Univerzita Karlova, Přírodovědecká fakulta, 2014)
    Date of defense: 16. 9. 2014
    Title: Solvent effects on ion pairing and photoionization in water Author: Mgr. et Ing. Eva Pluhařová Department: Physical and Macromoleculer Chemistry Advisor: Prof. Pavel Jungwirth, DSc., IOCB AS CR, v.v.i. Advisor's ...
  • Nové antimikrobiální peptidy izolované z jedu včel a studium mechanismu jejich účinku 

    Čujová, Sabína (Univerzita Karlova, Přírodovědecká fakulta, 2015)
    Date of defense: 4. 6. 2015
    EN The growing emergence of bacteria resistant to conventional antibiotics is very alarming. This has prompted an intensive search for alternative antimicrobial agents which kill bacteria with different modes of action ...
  • Divergent organohalide-respiring consortia in PCB-contaminated sediments 

    Mikešová, Martina (Univerzita Karlova, Přírodovědecká fakulta, 2016)
    Date of defense: 22. 9. 2016
    This study is focused on one particular group of the halogenated molecules called polychlorinated biphenyls (PCBs) - synthetic, organic compounds derived from biphenyl with bound chlorine atoms. Depending on the position ...
  • Mechanizmy aktivace a modulace vaniloidních TRP receptorů 

    Boukalová, Štěpána (Univerzita Karlova, Přírodovědecká fakulta, 2014)
    Date of defense: 12. 2. 2014
    Štěpána Boukalová Mechanisms of activation and modulation of vanilloid TRP channels TRPV1 and TRPV3 are thermosensitive ion channels from the vanilloid subfamily of TRP receptors. TRPV1, which is primarily expressed in ...
  • Electrochemical, photoelectrochemical and spectroelectrochemical characterization of nanomaterials 

    Pitňa Lásková, Barbora (Univerzita Karlova, Přírodovědecká fakulta, 2017)
    Date of defense: 16. 10. 2017
    Titanium dioxide (TiO2) and spinel Li4Ti5O12 belong to widely studied semiconducting metal oxides. Nanocrystalline TiO2 and Li4Ti5O12 are attractive materials for applications in Li-ion batteries and the former also for ...
  • Preparation and characterization of nanomaterials for electrochemical energy storage 

    Bouša, Milan (Univerzita Karlova, Přírodovědecká fakulta, 2017)
    Date of defense: 16. 10. 2017
    Graphene research is nowadays one of the worldwide most prominent fields of interest in material science due to many extraordinary properties of graphene and related materials. However, the different techniques of synthesis ...

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