This thesis investigates mammalian odorant-binding proteins (OBPs) us- ing a combination of computational approaches to understand their evo- lution, structural dynamics, and ligand recognition. First, sequence- and ...

- english Bear winter dormancy is a natural physiological adaptation to periods of food scarcity and adverse environmental conditions. In many respects, it resembles the hibernation observed in small mammals; however, key ...

High-resolution spatial transcriptomics reaches near single-cell level in sensitivity with additional spatial context. The downstream analysis re- mains fragmented across tools and data modalities, limiting reproducibility ...

High mountain areas represent highly dynamic environments with extreme conditions, making them particularly susceptible to geohazards. These potentially dangerous processes and phenomena can subsequently threaten human ...

In modern society we can observe shifting dietary patterns and an increase in high-sugar diets. Concurrently, a rise in mental illnesses and cognitive impairments at an early age can be observed. This thesis summarizes the ...