Diferenciace toxické psychózy a schizofrenní poruchy s důrazem na klinicky pozorovatelná specifika

Abstract

Background: In recent decades there has been a significant increase in the prevalence of substance-induced psychoses (SIP) in the Czech Republic. In the case of prolonged or recurrent SIP it often remains unclear whether to classify these conditions as chronic substance-induced psychoses or as schizophrenia. The etiology and nature of the psychosis play a crucial role in guiding treatment. From the perspective of addictology, emphasis is placed particularly on clinically observable characteristics. Objectives: The aim of this thesis is to systematically synthesize current knowledge in the field of differentiating between toxic psychoses and schizophrenia. Additionally, it seeks to develop a comparative case analysis to explore clinically observable aspects of SIP compared to schizophrenia, based on patients' retrospective experiences. Methods: The comparative case study uses the method of Very Similar Cases. It involves two participants with recurrent substance-induced psychotic episodes, of whom only one has been formally diagnosed with schizophrenia. Data collection was carried out through semi-structured interviews and thematic analysis was applied to process the data. Results: Despite a number of shared features and a significant symptom overlap, several distinctive differences were identified...

Background: In recent decades there has been a significant increase in the prevalence of substance-induced psychoses (SIP) in the Czech Republic. In the case of prolonged or recurrent SIP it often remains unclear whether to classify these conditions as chronic substance-induced psychoses or as schizophrenia. The etiology and nature of the psychosis play a crucial role in guiding treatment. From the perspective of addictology, emphasis is placed particularly on clinically observable characteristics. Objectives: The aim of this thesis is to systematically synthesize current knowledge in the field of differentiating between toxic psychoses and schizophrenia. Additionally, it seeks to develop a comparative case analysis to explore clinically observable aspects of SIP compared to schizophrenia, based on patients' retrospective experiences. Methods: The comparative case study uses the method of Very Similar Cases. It involves two participants with recurrent substance-induced psychotic episodes, of whom only one has been formally diagnosed with schizophrenia. Data collection was carried out through semi-structured interviews and thematic analysis was applied to process the data. Results: Despite a number of shared features and a significant symptom overlap, several distinctive differences were identified...