Kvalifikační práce
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Prediktivní faktory prekanceróz vulvy - optimalizace diagnosticko-terapeutického managementu
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 9. 11. 2022Vulvar cancer accounts for only 5% of gynaecological malignancies and belongs to uncommon gynaecological tumours. The incidence is around 4/100,000 women and the mortality reaches almost 2/100,000 women and has not changed ... -
Post-Translational Modifications of Nuclear and Non-Nuclear Proteins in Spermatozoa
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 29. 6. 2022Posttranslational modifications of nuclear and nonnuclear proteins in spermatozoa Summary The number of couples who need the help of assisted reproductive technology (ART) has increased over the years. Approximately half ... -
Molekulární biomarkery účinnosti protinádorových léčiv v experimentálních modelech a u pacientů se solidními nádory
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 23. 9. 2022Souhrn Karcinom ovarií je heterogenní skupinou onemocnění zpravidla epiteliálního původu. Naprostá většina diagnostikovaných případů je tzv. high-grade serózní karcinom, který tvoří přes 80 % všech odhalených případů. ... -
Kvantifikace mikrocév v histologiiStereologie mikrocév cévní stěny a mozku
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2021)Date of defense: 4. 6. 2021Considering the current knowledge on histology of microvessels suggested that quantification of the tissue microvessels itself should be accompanied by a description of the surrounding tissue components supplied by these ... -
Imunitní monitorace a imunoterapie po alogenní transplantaci krvetvorných kmenových buněk
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 27. 9. 2022Immune monitoring and adoptive immunotherapy following allogeneic hematopoietic stem cell transplantation - ABSTRACT Allogeneic hematopoietic stem cell transplantation (aloHSCT) is a specialized therapeutic method that is ... -
Brain oscillations and temporal structure of spatial memory pattern retrieval
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 29. 9. 2022The hippocampus is a brain structure essentially involved in episodic memory, spatial navigation and other complex cognitive functions. The distinct network architecture of hippocampal CA3 allows to combine converging ... -
Histologické hodnocení experimentálních modelů onemocnění jater
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 27. 9. 2022Animal models are widely used for research of liver diseases pathogenesis and progression and for development of new treatment strategies in hepatology. The dissertation thesis focuses on large animal model, specifically ... -
Psychiatric-relevant impairments in mouse models of spinocerebellar ataxias
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 29. 9. 2022Spinocerebellar ataxias (SCAs) constitute a heterogeneous group of diseases characterized by the dysfunction of the cerebellum and disturbed coordination of movements. Aside from these, many SCA patients suffer also from ... -
Vztah funkce míšních drah a šíře kanálu páteřního v závislosti na změně osy krční páteře
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 14. 9. 2022Introduction: The aim of our study was to assess the effect of dynamic changes in spinal flexion and extension assessed by dynamic magnetic resonance imaging(dMRI) on spinal cord functions assessed by dynamic evoked ... -
A Model for Optimizing Comprehensive Care for People With HIV Infection
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2022)Date of defense: 26. 9. 2022A model for optimizing comprehensive care for people with HIV infection Student: MUDr. Sam Hofman, MHA Supervisor: doc. MUDr. Dalibor Sedláček, CSc. Department of Infectious Diseases and Travel Medicine of the Faculty of ...
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