| dc.contributor.advisor | Kamlar, Martin | |
| dc.creator | Kurčina, Adam | |
| dc.date.accessioned | 2022-10-04T16:50:12Z | |
| dc.date.available | 2022-10-04T16:50:12Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11956/175254 | |
| dc.description.abstract | Phosphoinositides are naturally occurring molecules with vast range of biological activity important for cell life and survival. The exact role and mechanism of phosphatidylinositol 4,5-bisphosphate's actions are not yet elucidated. This bachelor's thesis is dedicated to the synthesis of selectively protected myo-inositol derivative suitable as precursor for synthesis of phosphatidylinositol 4,5-bisphosphate derivatives. Key words: Inositol, protective groups, regioisomers | en_US |
| dc.description.abstract | Fosfatidylinositoly sú látky vyskutujúce sa v prírode so širokou bioaktivitou potrebnou pre prežitie a život bunky. Mechanizmus pôsobenia a úloha fosphatidylinositol 4,5-bisfosfátu nie je zatiaľ jasná. Táto bakalárska práca sa venuje syntéze derivátu selektívne chráneného myo-inositolu, ktorý bude využitelný ako prekurzor k syntéze derivátov fosfatidylinositolu 4,5-bisfosfátu. Klíčová slova: Inositol, chránící skupiny, regioizomery | cs_CZ |
| dc.language | English | cs_CZ |
| dc.language.iso | en_US | |
| dc.publisher | Univerzita Karlova, Přírodovědecká fakulta | cs_CZ |
| dc.subject | Inositol | en_US |
| dc.subject | protective groups | en_US |
| dc.subject | regioisomers | en_US |
| dc.subject | Inositol | cs_CZ |
| dc.subject | chránící skupiny | cs_CZ |
| dc.subject | regioizomery | cs_CZ |
| dc.title | Preparation of myo-inositol derivatives | en_US |
| dc.type | bakalářská práce | cs_CZ |
| dcterms.created | 2022 | |
| dcterms.dateAccepted | 2022-06-07 | |
| dc.description.department | Department of Organic Chemistry | en_US |
| dc.description.department | Katedra organické chemie | cs_CZ |
| dc.description.faculty | Přírodovědecká fakulta | cs_CZ |
| dc.description.faculty | Faculty of Science | en_US |
| dc.identifier.repId | 242716 | |
| dc.title.translated | Příprava derivátů myo-inositolu | cs_CZ |
| dc.contributor.referee | Baszczyňski, Ondřej | |
| thesis.degree.name | Bc. | |
| thesis.degree.level | bakalářské | cs_CZ |
| thesis.degree.discipline | Medicinal Chemistry | en_US |
| thesis.degree.discipline | Medicinální chemie | cs_CZ |
| thesis.degree.program | Medicinal Chemistry | en_US |
| thesis.degree.program | Medicinální chemie | cs_CZ |
| uk.thesis.type | bakalářská práce | cs_CZ |
| uk.taxonomy.organization-cs | Přírodovědecká fakulta::Katedra organické chemie | cs_CZ |
| uk.taxonomy.organization-en | Faculty of Science::Department of Organic Chemistry | en_US |
| uk.faculty-name.cs | Přírodovědecká fakulta | cs_CZ |
| uk.faculty-name.en | Faculty of Science | en_US |
| uk.faculty-abbr.cs | PřF | cs_CZ |
| uk.degree-discipline.cs | Medicinální chemie | cs_CZ |
| uk.degree-discipline.en | Medicinal Chemistry | en_US |
| uk.degree-program.cs | Medicinální chemie | cs_CZ |
| uk.degree-program.en | Medicinal Chemistry | en_US |
| thesis.grade.cs | Výborně | cs_CZ |
| thesis.grade.en | Excellent | en_US |
| uk.abstract.cs | Fosfatidylinositoly sú látky vyskutujúce sa v prírode so širokou bioaktivitou potrebnou pre prežitie a život bunky. Mechanizmus pôsobenia a úloha fosphatidylinositol 4,5-bisfosfátu nie je zatiaľ jasná. Táto bakalárska práca sa venuje syntéze derivátu selektívne chráneného myo-inositolu, ktorý bude využitelný ako prekurzor k syntéze derivátov fosfatidylinositolu 4,5-bisfosfátu. Klíčová slova: Inositol, chránící skupiny, regioizomery | cs_CZ |
| uk.abstract.en | Phosphoinositides are naturally occurring molecules with vast range of biological activity important for cell life and survival. The exact role and mechanism of phosphatidylinositol 4,5-bisphosphate's actions are not yet elucidated. This bachelor's thesis is dedicated to the synthesis of selectively protected myo-inositol derivative suitable as precursor for synthesis of phosphatidylinositol 4,5-bisphosphate derivatives. Key words: Inositol, protective groups, regioisomers | en_US |
| uk.file-availability | V | |
| uk.grantor | Univerzita Karlova, Přírodovědecká fakulta, Katedra organické chemie | cs_CZ |
| thesis.grade.code | 1 | |
| uk.publication-place | Praha | cs_CZ |
| uk.thesis.defenceStatus | O | |
