Show simple item record

Psychosociální výhody substituční terapie u opiátů. Buprenorfin versus metadon
dc.contributor.advisorPáleníček, Tomáš
dc.creatorMarcussen, Bjarne Nicolay
dc.date.accessioned2018-09-13T10:19:34Z
dc.date.available2018-09-13T10:19:34Z
dc.date.issued2010
dc.identifier.urihttp://hdl.handle.net/20.500.11956/30067
dc.description.abstractSubstitution therapy has shown to be a very effective treatment strategy to reduce overdose related deaths and reducing the spread of HIV and Hepatitis C. It would be fair to say that substitution treatment is necessary and the most important part in the treatment process in opioid addiction also illustrated by the fact that it has become widely used. It is proven to be more effective than medication assisted detoxification and abrupt withdrawal treatment in reducing heroin use. The psychosocial benefits regarding employment, family relations and crime are evident. Methadone and buprenorphine are of different pharmacological natures and have different effects on the patient. It is generally claimed that buprenorphine has less of a euphoric effect, even though an increase in abuse has been reported in several countries. Buprenorphine is a safer drug than methadone due to its dosing ceiling effect, which virtually eliminates the danger over overdose. Both drugs show similar effect in terms of retention rates when given in high doses. Overall very little evidence so far exists that sustaining long-term abstinence after buprenorphine maintenance is any more likely than after methadone maintenance. It is likely to see substitution therapy programs being implemented on larger scale world wide as the foremost...en_US
dc.languageEnglishcs_CZ
dc.language.isoen_US
dc.publisherUniverzita Karlova, 3. lékařská fakultacs_CZ
dc.titlePsychosocial benefits of substitution therapy in opoid addicts. Buprenorphines versus Methadoneen_US
dc.typediplomová prácecs_CZ
dcterms.created2010
dcterms.dateAccepted2010-06-07
dc.description.departmentKlinika psychiatrie a lékařské psychologie - klinika psychiatriecs_CZ
dc.description.departmentDepartment of Psychiatry and Medical Psychology - Department of Psychiatryen_US
dc.description.facultyThird Faculty of Medicineen_US
dc.description.faculty3. lékařská fakultacs_CZ
dc.identifier.repId78544
dc.title.translatedPsychosociální výhody substituční terapie u opiátů. Buprenorfin versus metadoncs_CZ
dc.identifier.aleph001403686
thesis.degree.nameMUDr.
thesis.degree.levelmagisterskécs_CZ
thesis.degree.discipline-cs_CZ
thesis.degree.discipline-en_US
thesis.degree.programGeneral Medicineen_US
thesis.degree.programVšeobecné lékařstvícs_CZ
uk.thesis.typediplomová prácecs_CZ
uk.taxonomy.organization-cs3. lékařská fakulta::Klinika psychiatrie a lékařské psychologie - klinika psychiatriecs_CZ
uk.taxonomy.organization-enThird Faculty of Medicine::Department of Psychiatry and Medical Psychology - Department of Psychiatryen_US
uk.faculty-name.cs3. lékařská fakultacs_CZ
uk.faculty-name.enThird Faculty of Medicineen_US
uk.faculty-abbr.cs3.LFcs_CZ
uk.degree-discipline.cs-cs_CZ
uk.degree-discipline.en-en_US
uk.degree-program.csVšeobecné lékařstvícs_CZ
uk.degree-program.enGeneral Medicineen_US
thesis.grade.csVýborněcs_CZ
thesis.grade.enExcellenten_US
uk.abstract.enSubstitution therapy has shown to be a very effective treatment strategy to reduce overdose related deaths and reducing the spread of HIV and Hepatitis C. It would be fair to say that substitution treatment is necessary and the most important part in the treatment process in opioid addiction also illustrated by the fact that it has become widely used. It is proven to be more effective than medication assisted detoxification and abrupt withdrawal treatment in reducing heroin use. The psychosocial benefits regarding employment, family relations and crime are evident. Methadone and buprenorphine are of different pharmacological natures and have different effects on the patient. It is generally claimed that buprenorphine has less of a euphoric effect, even though an increase in abuse has been reported in several countries. Buprenorphine is a safer drug than methadone due to its dosing ceiling effect, which virtually eliminates the danger over overdose. Both drugs show similar effect in terms of retention rates when given in high doses. Overall very little evidence so far exists that sustaining long-term abstinence after buprenorphine maintenance is any more likely than after methadone maintenance. It is likely to see substitution therapy programs being implemented on larger scale world wide as the foremost...en_US
uk.file-availabilityV
uk.publication.placePrahacs_CZ
uk.grantorUniverzita Karlova, 3. lékařská fakulta, Klinika psychiatrie a lékařské psychologie - klinika psychiatriecs_CZ
thesis.grade.code1


Files in this item

Thumbnail
Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record


© 2017 Univerzita Karlova, Ústřední knihovna, Ovocný trh 560/5, 116 36 Praha 1; email: admin-repozitar [at] cuni.cz

Za dodržení všech ustanovení autorského zákona jsou zodpovědné jednotlivé složky Univerzity Karlovy. / Each constituent part of Charles University is responsible for adherence to all provisions of the copyright law.

Upozornění / Notice: Získané informace nemohou být použity k výdělečným účelům nebo vydávány za studijní, vědeckou nebo jinou tvůrčí činnost jiné osoby než autora. / Any retrieved information shall not be used for any commercial purposes or claimed as results of studying, scientific or any other creative activities of any person other than the author.

DSpace software copyright © 2002-2015  DuraSpace
Theme by 
@mire NV