Stanovení perzistentních organohalogenových polutantů metodou GC/MS/MS

Abstract

Conclusions o MSiMS methods for analysis of PCDD/Fs, PCBs, OCPs, and PBDES were develoPed o GC separations were optimized for MS/MS detection methods o GC/MS/MS optimized methods were validated. o Limits of quantification at level 0.1 - I pg/pl were achieved. o Linear response over four orders of magnitude was achieved except for some OCPs. o The selectivity of methods is better or comparable with a reference HRMS method' o Cost of GC/MS/MS analysis is significantly lower comPared to GC/HRMS o Developed methods were successfully applied for o Human blood, milk and adipose tissue analysis o Studies of de novo synthesis and destruďion of halogenated POP o In vitro study of PCB accumulation in human cells o List of application is enclosed Page 12