| dc.contributor.advisor | Pacáková, Věra | |
| dc.creator | Grabic, Roman | |
| dc.date.accessioned | 2018-04-12T12:41:11Z | |
| dc.date.available | 2018-04-12T12:41:11Z | |
| dc.date.issued | 2006 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11956/95741 | |
| dc.description.abstract | Conclusions o MSiMS methods for analysis of PCDD/Fs, PCBs, OCPs, and PBDES were develoPed o GC separations were optimized for MS/MS detection methods o GC/MS/MS optimized methods were validated. o Limits of quantification at level 0.1 - I pg/pl were achieved. o Linear response over four orders of magnitude was achieved except for some OCPs. o The selectivity of methods is better or comparable with a reference HRMS method' o Cost of GC/MS/MS analysis is significantly lower comPared to GC/HRMS o Developed methods were successfully applied for o Human blood, milk and adipose tissue analysis o Studies of de novo synthesis and destruďion of halogenated POP o In vitro study of PCB accumulation in human cells o List of application is enclosed Page 12 | en_US |
| dc.language | Čeština | cs_CZ |
| dc.language.iso | cs_CZ | |
| dc.publisher | Univerzita Karlova, Přírodovědecká fakulta | cs_CZ |
| dc.title | Stanovení perzistentních organohalogenových polutantů metodou GC/MS/MS | cs_CZ |
| dc.type | dizertační práce | cs_CZ |
| dcterms.created | 2006 | |
| dcterms.dateAccepted | 2006-06-28 | |
| dc.description.department | Department of Analytical Chemistry | en_US |
| dc.description.department | Katedra analytické chemie | cs_CZ |
| dc.description.faculty | Faculty of Science | en_US |
| dc.description.faculty | Přírodovědecká fakulta | cs_CZ |
| dc.identifier.repId | 198280 | |
| dc.title.translated | Determination of persistent organohalogen pollutants using GC/MS/MS methods | en_US |
| dc.contributor.referee | Ševčík, Jiří | |
| dc.contributor.referee | Matisová, Eva | |
| thesis.degree.name | Ph.D. | |
| thesis.degree.level | doktorské | cs_CZ |
| thesis.degree.discipline | - | en_US |
| thesis.degree.discipline | - | cs_CZ |
| thesis.degree.program | Analytická chemie | cs_CZ |
| thesis.degree.program | Analytical Chemistry | en_US |
| uk.thesis.type | dizertační práce | cs_CZ |
| uk.taxonomy.organization-cs | Přírodovědecká fakulta::Katedra analytické chemie | cs_CZ |
| uk.taxonomy.organization-en | Faculty of Science::Department of Analytical Chemistry | en_US |
| uk.faculty-name.cs | Přírodovědecká fakulta | cs_CZ |
| uk.faculty-name.en | Faculty of Science | en_US |
| uk.faculty-abbr.cs | PřF | cs_CZ |
| uk.degree-discipline.cs | - | cs_CZ |
| uk.degree-discipline.en | - | en_US |
| uk.degree-program.cs | Analytická chemie | cs_CZ |
| uk.degree-program.en | Analytical Chemistry | en_US |
| thesis.grade.cs | Prospěl | cs_CZ |
| thesis.grade.en | Pass | en_US |
| uk.abstract.en | Conclusions o MSiMS methods for analysis of PCDD/Fs, PCBs, OCPs, and PBDES were develoPed o GC separations were optimized for MS/MS detection methods o GC/MS/MS optimized methods were validated. o Limits of quantification at level 0.1 - I pg/pl were achieved. o Linear response over four orders of magnitude was achieved except for some OCPs. o The selectivity of methods is better or comparable with a reference HRMS method' o Cost of GC/MS/MS analysis is significantly lower comPared to GC/HRMS o Developed methods were successfully applied for o Human blood, milk and adipose tissue analysis o Studies of de novo synthesis and destruďion of halogenated POP o In vitro study of PCB accumulation in human cells o List of application is enclosed Page 12 | en_US |
| uk.file-availability | P | |
| uk.publication.place | Praha | cs_CZ |
| uk.grantor | Univerzita Karlova, Přírodovědecká fakulta, Katedra analytické chemie | cs_CZ |
