| dc.contributor.advisor | Bláha, Pavel | |
| dc.creator | Zamrazilová, Hana | |
| dc.date.accessioned | 2019-05-03T18:17:30Z | |
| dc.date.available | 2019-05-03T18:17:30Z | |
| dc.date.issued | 2009 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11956/31253 | |
| dc.description.abstract | L. Abstrakt Background: Theprevalenceof obesityhasoverthe pasttwentyyearsgrownto suchanextentthat it is now commonlyrefenedto as a pandemic.From the point of view of healthrisks and complicationsconnectedwith obesity,the fact that this increasingtrend is prominenteven in childrenseemsto beveryserious.Thestudieshaveprovedclearrelationsbetweenearlyobesityand obesitypersistinguntil adulthood,the amountof visceralfat, cardiovascularrisks,diabetestype2, hypertensionandhyperlipidemia. Aims: To detect weight changesand body compositionchangesin children during the comprehensive5-6 weekin-patientweightreducingprogramme.To comparethe amountof body fat determinedby anthropomehicmethodsandDEXA method.To evaluateselectedbiochemical and hormonal parametersof lipid and glucosemetabolismsin obesechildren. To detectthe dependenceof anthropometricand biochemicalparameterson polymorphismsprolgl9pro, Ser343SerandGln2?3Argof the LEPRgene,andpolymorphismLeul62Valof theppARalfagene. Results: The study showed significant difftrences in body weight decreasesexpressedin percentagefromtheinitialbodyweightin thegroupof obesegirls(p & 0.001).Girlsthelowestage category(7-9 years)hadsignificantlygreaterweightlossescomparedto theirweightat thestartof theirstay,opposedto girlsin higheragecategories(11-17years,p & 0.05).At thebeginningof... | en_US |
| dc.description.abstract | 1. Abstrakt fvod: Prevalenceobezitydosahlab€hemposlednichdvacetilet takov;ichrozmEr&,Zeje bdZnd nazyvtnapandemii.Z hlediskazdravotnichrizik a komplikacis obezitouspojenfchsejako velmi ziyahnyjevifakt,Zetentostoupajicitrendje markantnfiv ddtskdpopulaci.Studieprokazujijasn6 souvislostimezi dasnouobezitoua obezitoupfetrv6vajicido dospdlosti,mnoZstvimviscer6lniho tuku,kardiovaskul6rnimrrrzilq,diabetem2. typu,hypertenziahyperlipidemii. Cile: Zjistit hmotnostnizmdnyazmEnyv tdlesnemsloZeniu ddtiabsolvujicich5-6tydenniledebnd redukdnipobyt. PorovnatmnoZstvitdlesnehotuku stanovendhoantropometrickfmimetodamia metodouDEXA. Zhodnotitvybrandbiochemickda hormonillniparametrycharakterizujicilipidovi a gluk6zovf metabolismusu obdznichddti. PorovnathodnotyIGF-I a IGFBP3 u obdznicha Stihlfchddti.Zjistit vliv polymorfismfiProl0l9Pro, Ser343Sera Gln223Argv genuproLEPRa polymorfismuLeu162Valv genu pro PPARalfana parametrysledovandv prubdhuredukdniho programu. Metodikaa soubor:Do studiebyly zahrnutydEtive vEku7-18 let(345divek,180chlapc&),ktere seridastnily5-6tfdenniholddebndhoredukdnihopobytuv L6debn6Dr. L. Filipav PodEbradech. Sledovanybyly antropologickd,biochemickd,hormon6,lnia genetickdparametry.Statistickii analyzadatbylaprovedenav programechStatistica6.0,NCSS?7aAntropo. Vfsledky: Do5lok... | cs_CZ |
| dc.language | Čeština | cs_CZ |
| dc.language.iso | cs_CZ | |
| dc.publisher | Univerzita Karlova, Přírodovědecká fakulta | cs_CZ |
| dc.title | Změny tělesného složení obézních dětí během redukčního procesu. Studium vybraných kandidátních genů pro obezitu a jejich asociací s antropometrickými a biochemickými parametry. | cs_CZ |
| dc.type | dizertační práce | cs_CZ |
| dcterms.created | 2009 | |
| dcterms.dateAccepted | 2009-09-29 | |
| dc.description.department | Department of Anthropology and Human Genetics | en_US |
| dc.description.department | Katedra antropologie a genetiky člověka | cs_CZ |
| dc.description.faculty | Faculty of Science | en_US |
| dc.description.faculty | Přírodovědecká fakulta | cs_CZ |
| dc.identifier.repId | 77153 | |
| dc.title.translated | Body composition changes in obese children during the weight reducing programme. The study of selected candidate genes for obesity and their associations with anthropometric and biochemical parameters. | en_US |
| dc.contributor.referee | Štich, Vladimír | |
| dc.contributor.referee | Brdička, Radim | |
| dc.identifier.aleph | 002057073 | |
| thesis.degree.name | Ph.D. | |
| thesis.degree.level | doktorské | cs_CZ |
| thesis.degree.discipline | - | cs_CZ |
| thesis.degree.discipline | - | en_US |
| thesis.degree.program | Antropologie | cs_CZ |
| thesis.degree.program | Anthropology | en_US |
| uk.thesis.type | dizertační práce | cs_CZ |
| uk.taxonomy.organization-cs | Přírodovědecká fakulta::Katedra antropologie a genetiky člověka | cs_CZ |
| uk.taxonomy.organization-en | Faculty of Science::Department of Anthropology and Human Genetics | en_US |
| uk.faculty-name.cs | Přírodovědecká fakulta | cs_CZ |
| uk.faculty-name.en | Faculty of Science | en_US |
| uk.faculty-abbr.cs | PřF | cs_CZ |
| uk.degree-discipline.cs | - | cs_CZ |
| uk.degree-discipline.en | - | en_US |
| uk.degree-program.cs | Antropologie | cs_CZ |
| uk.degree-program.en | Anthropology | en_US |
| thesis.grade.cs | Prospěl/a | cs_CZ |
| thesis.grade.en | Pass | en_US |
| uk.abstract.cs | 1. Abstrakt fvod: Prevalenceobezitydosahlab€hemposlednichdvacetilet takov;ichrozmEr&,Zeje bdZnd nazyvtnapandemii.Z hlediskazdravotnichrizik a komplikacis obezitouspojenfchsejako velmi ziyahnyjevifakt,Zetentostoupajicitrendje markantnfiv ddtskdpopulaci.Studieprokazujijasn6 souvislostimezi dasnouobezitoua obezitoupfetrv6vajicido dospdlosti,mnoZstvimviscer6lniho tuku,kardiovaskul6rnimrrrzilq,diabetem2. typu,hypertenziahyperlipidemii. Cile: Zjistit hmotnostnizmdnyazmEnyv tdlesnemsloZeniu ddtiabsolvujicich5-6tydenniledebnd redukdnipobyt. PorovnatmnoZstvitdlesnehotuku stanovendhoantropometrickfmimetodamia metodouDEXA. Zhodnotitvybrandbiochemickda hormonillniparametrycharakterizujicilipidovi a gluk6zovf metabolismusu obdznichddti. PorovnathodnotyIGF-I a IGFBP3 u obdznicha Stihlfchddti.Zjistit vliv polymorfismfiProl0l9Pro, Ser343Sera Gln223Argv genuproLEPRa polymorfismuLeu162Valv genu pro PPARalfana parametrysledovandv prubdhuredukdniho programu. Metodikaa soubor:Do studiebyly zahrnutydEtive vEku7-18 let(345divek,180chlapc&),ktere seridastnily5-6tfdenniholddebndhoredukdnihopobytuv L6debn6Dr. L. Filipav PodEbradech. Sledovanybyly antropologickd,biochemickd,hormon6,lnia genetickdparametry.Statistickii analyzadatbylaprovedenav programechStatistica6.0,NCSS?7aAntropo. Vfsledky: Do5lok... | cs_CZ |
| uk.abstract.en | L. Abstrakt Background: Theprevalenceof obesityhasoverthe pasttwentyyearsgrownto suchanextentthat it is now commonlyrefenedto as a pandemic.From the point of view of healthrisks and complicationsconnectedwith obesity,the fact that this increasingtrend is prominenteven in childrenseemsto beveryserious.Thestudieshaveprovedclearrelationsbetweenearlyobesityand obesitypersistinguntil adulthood,the amountof visceralfat, cardiovascularrisks,diabetestype2, hypertensionandhyperlipidemia. Aims: To detect weight changesand body compositionchangesin children during the comprehensive5-6 weekin-patientweightreducingprogramme.To comparethe amountof body fat determinedby anthropomehicmethodsandDEXA method.To evaluateselectedbiochemical and hormonal parametersof lipid and glucosemetabolismsin obesechildren. To detectthe dependenceof anthropometricand biochemicalparameterson polymorphismsprolgl9pro, Ser343SerandGln2?3Argof the LEPRgene,andpolymorphismLeul62Valof theppARalfagene. Results: The study showed significant difftrences in body weight decreasesexpressedin percentagefromtheinitialbodyweightin thegroupof obesegirls(p & 0.001).Girlsthelowestage category(7-9 years)hadsignificantlygreaterweightlossescomparedto theirweightat thestartof theirstay,opposedto girlsin higheragecategories(11-17years,p & 0.05).At thebeginningof... | en_US |
| uk.file-availability | V | |
| uk.publication.place | Praha | cs_CZ |
| uk.grantor | Univerzita Karlova, Přírodovědecká fakulta, Katedra antropologie a genetiky člověka | cs_CZ |
| thesis.grade.code | P | |
| dc.identifier.lisID | 990020570730106986 | |
