• Pohyb pánve při lokomoci člověka 

      Defence status: DEFENDED
      Hakrová, Kristýna (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      Previous studies focused on pelvic rotation in relation to step length suggest that (notwithstanding a few other factors) step length is influenced by pelvic rotation. This mechanism is closely linked to australopithecines ...
    • Analýza tématu buněčná biologie v českých učebnicích přírodopisu 

      Defence status: DEFENDED
      Zupko, Jakub (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      Cell biology is a dynamic but also complex and abstract scientific field. Therefore, it is crucial that teachers have sufficient quality teaching material to teach it. This paper aims to assess the quality of the cell ...
    • Nádorová onemocnění a jejich zařazení do výuky biologie na střední škole 

      Defence status: DEFENDED
      Baudyšová, Alžběta (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      Nowadays, cancer is one of the most common causes of death in developed countries. Despite the increased media coverage of the illness not all high school students are able to describe why and how tumours are developed and ...
    • Influence of lamin A/C on paternal pronucleus DNA demethylation 

      Defence status: DEFENDED
      Václavková, Vendula (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      A series of dynamic epigenetic changes need to happen to rebuild the gamete's genome after fertilization and to secure the totipotency of the zygote. The processes can be observed in both parental pronuclei, although the ...
    • CRISPR/Cas9 editing of leukemic B-cells: searching for microRNA-155 targets involved in the process of leukemogenesis 

      Defence status: NOT DEFENDED
      Sypecká, Markéta (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      CRISPR/Cas9 editing of leukemic B-cells: searching for microRNA-155 targets involved in the process of leukemogenesis Introduction: Chronic lymphocytic leukemia (chronic lymphoid leukemia, CLL) is a monoclonal disorder ...
    • Opravy DNA v oocytech a preimplantačních embryích 

      Defence status: DEFENDED
      Whole item or its parts have restricted access until 07. 06. 2025
      Koubovská, Markéta (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      Our diploma thesis focused on the effect of hormonal stimulation on DNA integrity of mammals' oocytes. Later, we also focused on its effect on DNA integrity on mammals' embryos and their developmental potential. Maintaining ...
    • In vitro selekce aptamerů pro methioninsulfoxid 

      Defence status: DEFENDED
      Jureček, Matěj (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      Oxidation of methionine to methionine sulfoxide in proteins is considered one of important post-translational modifications of proteins. This modification can activate and also inhibit functions of many proteins and it is ...
    • Imunomodulační potenciál progenitorů Sertoliho buněk u pulců rodu Xenopus v rámci hojení amputovaného ocasu 

      Defence status: DEFENDED
      Mertová, Irem (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      A cell culture of common Sertoli and peritubular myoid cells progenitors derived from the testes of male X. tropicalis, called XtiSC, was established in the Laboratory of Developmental Biology. XtiSCs exhibit similar ...
    • Distanční praktická výuka a učení 

      Defence status: DEFENDED
      Zdobinská, Helena (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      This diploma thesis describes practical activities and related topics during forced distant education due to COVID-19 pandemic. In the theoretical part of thesis, the distant education is defined. I also described some of ...
    • Biochemical tools for targeting immunomodulatory receptor CD73 

      Defence status: DEFENDED
      Whole item or its parts have restricted access until 07. 06. 2025
      Poukarová, Magdalena (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      New approaches to cancer treatment are investigated because cancer remains one of the most abundant causes of death. One of the promising fields of oncology is immunotherapy, which is based on the activation of immunity ...
    • Stimulation of mesenchymal stem cells osteogenic differentiation using perfusion bioreactor 

      Defence status: DEFENDED
      Šljivnjak, Erna (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      Bone cells in vivo reside in a dynamic environment exposed to constant chemical and mechanical stimuli caused by the interstitial fluid flow. It is hypothesized that perfusion of the medium through the scaffold increases ...
    • Lokalizace maternálních RNA ve vajíčcích a časných embryích 

      Defence status: DEFENDED
      Šimková, Kateřina (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      The asymmetric localization of maternal RNAs and proteins is a crucial mechanism for the body plan development in many animal species. These maternal factors are expressed during the oogenesis and they are used for the ...
    • Characterization of closed mitosis in the fission yeast Schizosaccharomyces pombe with perturbed lipid metabolism 

      Defence status: DEFENDED
      Hohoš, Patrik (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 7. 6. 2022
      [EN] The division of an eukaryotic cell is mediated by the process of mitosis. It is a complex cellular process which needs to be highly regulated. In contrast to the mammalian open type of mitosis when nuclear envelope ...
    • Potravinový deficit v rozvojových zemích: faktory vzniku, regionální diferenciace, možná řešení 

      Defence status: DEFENDED
      Ližanová, Iveta (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      This bachelor's thesis deals with food deficit issues in developing countries. First and foremost, it is dedicated to defining basic concepts that explain the food deficit. It then looks at the range of individual food ...
    • Modulační působení kmenových buněk na buňky imunitního systému zprostředkované mitochondriálním transferem 

      Defence status: DEFENDED
      Somova, Veronika (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      Stem cells use different mechanisms of intercellular communication to modulate an immune response. Mitochondrial transfer is one of the mechanisms which induce metabolic changes, support cell survival, and change the ...
    • Dopad 1. vlny pandemie Covid-19 na dopravní obslužnost obcí Česka 

      Defence status: DEFENDED
      Procházková, Kristina (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      Covid-19 pandemic affected the whole world in short period of time. Big impact was registered by transportation sector. Public transport was affected by Covid-19 disease as soon as it started spreading. This thesis observes ...
    • Analýza turismu v archeologické památce Machu Picchu 

      Defence status: DEFENDED
      Břežná, Tereza (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      This bachelor thesis is an overview of the analysis of tourism in the archaeological monument of Machu Picchu with a focus on overturism. Tourism is an ever-evolving sector that brings both positive and negative aspects ...
    • Outdoorová vzdělávací hra na téma dělicích metod pro žáky ZŠ 

      Defence status: DEFENDED
      Kydalová, Radka (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      The Covid-19 pandemic in 2020 and 2021 had a particularly severe impact on teaching in all types of schools, especially in the Czech Republic. Science lessons could not actively develop the practical skills of pupils, who ...
    • Diagnostický potenciál extracelulárních vesikulů 

      Defence status: DEFENDED
      Klementová, Helena (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      Extracellular vesicles (EV) are membrane particles produced by cells. Many published papers describe changes in the level of EV in body fluids under various pathological conditions. In our study, we analyzed the numbers ...
    • Úloha metabolismu fibroblastů plicní adventicie v aktivaci imunitního systému během vývoje plicní arteriální hypertenze 

      Defence status: DEFENDED
      Křivonosková, Monika (Univerzita Karlova, Přírodovědecká fakulta, 2022)
      Date of defense: 6. 6. 2022
      The development of inflammation in the small distal pulmonary vessels plays an important role in the development of pulmonary arterial hypertension (PAH). One of the cell types found in the pulmonary vessels are fibroblasts, ...

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