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Diagnostika neurodegenerativních chorob pomocí Ramanovy spektroskopie
Diagnostics of neurodegenerative diseases by means of Raman spectroscopy
diploma thesis
Advisor: Kopecký, Vladimír
Date Issued:
Date of defense: 30. 05. 2011
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: Léčba neurodegenerativních chorob je často velmi obtížná a její úspěšnost závisí na včasné diagnóze. Proto jsme v této práci vyvíjeli novou diagnostickou metodu roztroušené sklerózy a Alzheimerovy nemoci pomocí Ramanovy ...
Therapies of neurodegenerative diseases are often very difficult and their success depend on an early diagnose. From that reason we have been developing new diagnostic method for multiple sclerosis and Alzheimer disease ...
Therapies of neurodegenerative diseases are often very difficult and their success depend on an early diagnose. From that reason we have been developing new diagnostic method for multiple sclerosis and Alzheimer disease ...
Studium biomolekul pomocí povrchem zesílené Ramanovy mikrospektroskopie
Study of biomolecules by Surface-enhanced Raman microspectroscopy
diploma thesis
Advisor: Procházka, Marek
Date Issued:
Date of defense: 14. 09. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: Práce se zabývá studiem biomolekul pomocí mikrospektroskopie povrchem zesíleného Ramanova rozptylu (SERS). K tomuto účelu byly testovány povrchy na bázi zlatých a stříbrných koloidních nanočástic imobilizovaných buď pomocí ...
This work deals with study of biomolecules using surface-enhanced Raman scattering (SERS) microspectroscopy. For that purpose surfaces based on gold and silver colloidal nanoparticles immobilized either by silane or by ...
This work deals with study of biomolecules using surface-enhanced Raman scattering (SERS) microspectroscopy. For that purpose surfaces based on gold and silver colloidal nanoparticles immobilized either by silane or by ...
Mikrokalorimetrické studium termodynamické stability hybridních komplexů nukleových kyselin
Thermodynamic Stability of Hybrid Nucleic Acid Complexes: Microcalorimetric Study
diploma thesis
Advisor: Štěpánek, Josef
Date Issued:
Date of defense: 14. 09. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: Práce se zabývá aplikací diferenční skenovací kalorimetrie (DSC) pro studium potenciálních oligonukleotidových terapeutik. Byly stanoveny možnosti i limity použitého DSC přístroje a stanovené optimální podmínky pro měření ...
This work deals with implementation of differential scanning kalorimetry (DSC) into research of potential oligonucleotide therapeutics. Capabilities and limits of the DSC device have been determined and optimal conditions ...
This work deals with implementation of differential scanning kalorimetry (DSC) into research of potential oligonucleotide therapeutics. Capabilities and limits of the DSC device have been determined and optimal conditions ...
Strukturní flexibilita regulačního segmentu DNA
Structural flexibility of regulatory DNA element
diploma thesis
Advisor: Štěpánek, Josef
Date Issued:
Date of defense: 14. 09. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: Transcription of the genetic code is controlled by numerous proteins. Some of them, so-called transcription factors, bind to certain DNA regions possessing anomalous properties due to their specific and highly conservative ...
Molekulárně-dynamické simulace komplexů sestávajících z proteinů a nukleových kyselin
Molecular dynamics simulations of complexes consisting of proteins and nucleic acids
diploma thesis
Advisor: Barvík, Ivan
Date Issued:
Date of defense: 20. 05. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: V rámci diplomová práce byly prostudovány algoritmy numerické integrace. Poté byla provedena důkladná studie aktivních míst polymeras virů HCV a HIV v komplexech s přirozeným substrátem a komplexem, ve kterém byl přistupující ...
At first, numerical integration algorithms was studied. Main objective was a study of active sites of HCV and HIV polymerases in complexes with a natural substrate and in complexes where an approaching nucleosidetriphosphate ...
At first, numerical integration algorithms was studied. Main objective was a study of active sites of HCV and HIV polymerases in complexes with a natural substrate and in complexes where an approaching nucleosidetriphosphate ...
Metabolický profil lidského mozku in vivo v MR obraze a spektru
Metabolic profile of human brain in vivo in MR image and spectrum
diploma thesis
Advisor: Hájek, Milan
Date Issued:
Date of defense: 11. 09. 2007
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: Magnetic resonance imaging and spectroscopic imaging have proven to be useful to monitor a metabolism in the human brain. The thesis is concerned to repeatability and reproducibility of spectroscopic data measured on 1.5T ...
Optické vlastnosti vázaných kvantových jam v magnetickém poli
Optical properties of coupled quantum wells in magnetic field
diploma thesis
Advisor: Grill, Roman
Date Issued:
Date of defense: 14. 05. 2007
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract not found
Molekulárně-dynamické simulace komplexů nukleových kyselin enzymu RNase H
MD simulations of complexes between nucleic acids and RNase H
diploma thesis
Advisor: Barvík, Ivan
Date Issued:
Date of defense: 25. 05. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: The aim of this diploma thesis was to study interactions between human Rase H enzyme and a natural and modified substrate using molecular dynamics simulations (altogether 9 MD runs ere produced). Conformational preferences ...
Studium transportních proteinů z rodiny Nramp
Study of transport proteins of the Nramp family
diploma thesis
Advisor: Chaloupka, Roman
Date Issued:
Date of defense: 25. 05. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: The Natural Resistance-Associated Macrophage Proteins (Nramp) form functionally conserved family of proton-dependent divalent metal ion transporters. In the present study, we investigated transport properties of a prokaryotic ...
Tenké scintilační vrstvy pro 2D zobrazení
Novel thin scintillation films for 2D imaging screens
diploma thesis
Advisor: Kučera, Miroslav
Date Issued:
Date of defense: 12. 05. 2009
Faculty / Institute: Matematicko-fyzikální fakulta / Faculty of Mathematics and Physics
Abstract: V této práci jsme se zaměřili na zkoumání vlastností scintilačních vrstev cerem dotovaných granátů (CexLu3-xAl5O12, CexY3-xAl5O12) připravených metodou izotermální kapalné epitaxe. Tento scintilační materiál se vyznačuje ...
In this work we studied properties of Ce doped garnet scintillator layers (CexLu3-xAl5O12, CexY3-xAl5O12). They were prepared by liquid phase epitaxy. Studied materials show fast response, high quantum efficiency and good ...
In this work we studied properties of Ce doped garnet scintillator layers (CexLu3-xAl5O12, CexY3-xAl5O12). They were prepared by liquid phase epitaxy. Studied materials show fast response, high quantum efficiency and good ...