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A study of beta-adrenergic myocardial signaling in spontaneously hypertensive rat of transgenic strain SHR-Tg19
Studium beta-adrenergní signalizace v myokardu spontánně hypertenzního potkana transgenního kmene SHR-Tg19
diploma thesis
Advisor: Novotný, Jiří
Date Issued:
Date of defense: 10. 09. 2012
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract: β-adrenergní signalizace hraje důležitou roli v srdci, kde reguluje srdeční frekvence a kontraktilitu. Má určitý vliv na rozvoj hypertenze a srdeční hypertrofií. Jako model pro lidské esenciální hypertenze často se používá ...
β-Adrenergic signalization plays an important role in heart, regulating cardiac frequency and contractility. It is also involved in development of hypertension and heart hypertrophy. Spontaneous hypertensive rat strain is ...
β-Adrenergic signalization plays an important role in heart, regulating cardiac frequency and contractility. It is also involved in development of hypertension and heart hypertrophy. Spontaneous hypertensive rat strain is ...
Mechanismy mateřské synchronizace fetálních cirkadiánních hodin
Mechanisms of maternal entrainment of the fetal circadian clock
diploma thesis
Advisor: Sumová, Alena
Date Issued:
Date of defense: 07. 09. 2017
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract: Naše tělo je vystavené velkému množství cyklických změn ve svém okolí, jako je například střídání dne a noci nebo ročních období. Aby mohl organismus tyto změny předvídat a včas na ně reagovat, je vybaven vnitřními hodinami, ...
Our body is influenced by many cyclical changes in the environment, such as day and night or seasons. To predict these changes and react to them in time, the organism is equipped with inner clock, which rhythmically ...
Our body is influenced by many cyclical changes in the environment, such as day and night or seasons. To predict these changes and react to them in time, the organism is equipped with inner clock, which rhythmically ...
Vliv endotoxinu lipopolysacharidu na cirkadiánní systém
The influence of endotoxin lipopolysaccharide on the circadian system
diploma thesis
Advisor: Bendová, Zdeňka
Date Issued:
Date of defense: 02. 06. 2015
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract: Biologické hodiny jsou zodpovědné za řízení cirkadiánních rytmů v řadě fyziologických a behaviorálních funkcí, včetně aktivity imunitního systému. U savců jsou tyto hodiny uloženy v suprachiasmatických jádrech hypothalamu ...
The biological clock are responsible for entraining of circadian rhytms in many physiological and behavioral functions, including the activity of immune system. In mammals, the biological clock are located in the suprachiasmatic ...
The biological clock are responsible for entraining of circadian rhytms in many physiological and behavioral functions, including the activity of immune system. In mammals, the biological clock are located in the suprachiasmatic ...
Studium signalizace a cytoprotektivního potenciálu kanabinoidních GPR55 receptorů v PC12 buňkách
A study of signaling and cytoprotective potential of cannabinoid GPR55 receptors in PC12 cells
diploma thesis
Advisor: Novotný, Jiří
Date Issued:
Date of defense: 12. 09. 2016
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract: Koncem 20. století bylo známo, že kanabinoidní látky interagují se dvěma receptory, CB1 a CB2. Následné farmakologické studie však potvrdily, že existují další receptory vážící kanabinoidy. GPR55 je transmembránový s G ...
At the end of the 20th century it was known that cannabinoid drugs interact with two receptors, CB1 and CB2. Subsequent pharmacological studies have confirmed that there are other receptors interacting with cannabinoids. ...
At the end of the 20th century it was known that cannabinoid drugs interact with two receptors, CB1 and CB2. Subsequent pharmacological studies have confirmed that there are other receptors interacting with cannabinoids. ...
Studium vlivu β-1,3-glukanu aplikovaného v dlouhodobém pitném programu na vybrané imunitní parametry
Study of the influence of β-1,3-glucan applied in long-lasting drinking programme on selected immune parametres
diploma thesis
Advisor: Šíma, Petr
Date Issued:
Date of defense: 05. 06. 2006
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract not found
Sérové markery aktivity cholesterol 7α hydroxylasy.
Serum markers of cholesterol 7α hydroxylase activity
diploma thesis
Advisor: Leníček, Martin
Date Issued:
Date of defense: 01. 06. 2017
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract: Cholesterol 7-hydroxyláza (CYP7A1) je hlavní limitní enzym klasické dráhy syntézy žlučových kyselin (BA), kterou je u člověka katabolizována přibližně polovina cholesterolu. Stanovení enzymatické aktivity CYP7A1 je klíčovým ...
Cholesterol 7-hydroxylase (CYP7A1) is the rate limiting enzyme of the classical pathway of bile acid (BA) synthesis, which catabolizes approximately half of cholesterol in man. Determination of CYP7A enzymatic activity is ...
Cholesterol 7-hydroxylase (CYP7A1) is the rate limiting enzyme of the classical pathway of bile acid (BA) synthesis, which catabolizes approximately half of cholesterol in man. Determination of CYP7A enzymatic activity is ...
Vliv obstrukční spánkové apnoe na oxidaci a transport mastných kyselin v kosterním svalu pacientů s diabetes mellitus 2. typu
Effect of obstructive sleep apnea on oxidation and transport of fatty acids in skeletal muscle in patients with type 2 diabetes mellitus
diploma thesis
Advisor: Polák, Jan
Date Issued:
Date of defense: 27. 05. 2019
Faculty / Institute: Přírodovědecká fakulta / Faculty of Science
Abstract: Syndrom spánkové apnoe neboli spánkový apnoický syndrom je závažné onemocnění, které ohrožuje pacienty vysokým rizikem rozvoje kardiovaskulárních chorob. Jedná se o onemocnění charakterizované poruchou dýchání projevující ...
Sleep apnea syndrome, or sleep apneic syndrome, is a serious illness that causes a high risk of cardiovascular disease development in patients. This disease is characterized by a breathless breathing disorder and falls ...
Sleep apnea syndrome, or sleep apneic syndrome, is a serious illness that causes a high risk of cardiovascular disease development in patients. This disease is characterized by a breathless breathing disorder and falls ...