1. lékařská fakulta
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Habilitační práce [71]
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Habilitační práce obhajované před rokem 2006 [1]
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Kvalifikační práce [4257]
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Kvalifikační práce obhajované před rokem 2006 [0]
Theses defended before year 2006
Recent Submissions
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Interplay between ghrelin and its novel endogenous antagonist LEAP2: possible role in the pathology of obesity
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 5. 10. 2023The increasing number of overweight and obese individuals has become a major health issue in our society. The etiology of obesity often involves excessive hyperphagia, highlighting the importance of comprehensive understanding ... -
Fluorescent Nanoprobes Emitting in Near-Infrared Region for Biomedical Applications
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 5. 10. 2023The primary focus of this thesis is to conduct an in-depth investigation into the capabilities of near-infrared photoluminescent (PL) nanoprobes and their application in biomedicine. Specifically, this research explores ... -
Vliv složení mastných kyselin v lipidech séra a/nebo tukové tkáni na metabolismus lipidů a sacharidů u obézních osob různých věkových kategorií
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 21. 9. 2023Obesity is a chronic disease that is caused by many factors. Excessive adipose tissue is involved in the development of metabolic and cardiovascular diseases. Prevention of cardiometabolic risks includes lifestyle arrangement, ... -
Molekulární mechanizmy propojení dysfunkce tukové tkáně a aterosklerotických komplikací
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 21. 9. 2023Obesity and its associated comorbidities increase the risk of mortality. The development of subclinical inflammation associated with obesity also plays a significant role in this. In our work, we focused on changes in the ... -
Functional and Pathophysiological-morphological Correlates of Neurodegenerative Diseases
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 4. 9. 2023This doctoral thesis pictures neurodegenerative diseases as a multilevel process, describes various correlates on each pathophysiological level, and presents selected correlates in Huntington's disease and mitochondrial ... -
Užití transkraniální stimulace stejnosměrným proudem v léčbě tinitu a jeho psychických komorbidit
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 5. 9. 2023The theoretical part of our work is divided into three chapters and provides a contemporary systematic literature review of tinnitus, neurostimulation, and selected neurostimulation methods in its therapy. The first chapter ... -
Neurologické projevy Fabryho nemoci
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 4. 9. 2023Neurological manifestations of Fabry disease Abstract The presented thesis deals with cerebrovascular manifestations of a rare X-linked disease, Fabry disease (FD). Screening programs can detect unrecognized disease and ... -
Neurologické projevy u lyzozomálně střádavých onemocnění
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 5. 9. 2023Objective: Lysosomal storage disorders (LSD) represent a rare cause of neurologic impairment in childhood and adulthood. The aim of our study was to characterize patients with late-onset form of Tay-Sachs disease (LOTS) ... -
Výskyt neurodegenerativních onemocnění u pacientů s achalázií jícnu
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 4. 9. 2023Introduction: Achalasia is a primary motility disorder of the esophagus due to degeneration neurons in myenteric plexus. Although the exact pathogenesis is unknown, autoimmune and neurodegenerative processes seem to be ... -
Historický vývoj léčby závislosti na alkoholu v Psychiatrické léčebně v Dobřanech do roku 1989
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Background Abstract: Medical care for addicts began to develop in the territory of the Czech Republic after 1911. The foundation of the Apolinar established a pivotal treatment procedure. Subsequent medical facilities did ... -
Užívání návykových látek v prostředí nočního života
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Background: The nightlife environment is associated with a higher prevalence of substance use compared to the general population. This use is typically recreational. Patterns of use, frequency and motivation tend to be ... -
Problémové sledování internetové pornografie v souvislosti se sociální fobiíí
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023(v AJ) Internet porngraphy offers immediate sexual pleasure without much effort. Pornography also provides almost unlimited content and the possibility of watching harder pornography when soft pornography doesn't meet one's ... -
Vliv ústavní léčby na fenomén sebehodnocení pacientů léčících se ze závislosti na oddělení léčby závislostí Psychiatrické nemocnice Kosmonosy
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Baseline: Self-esteem is often perceived as an indicator of emotional and mental well-being and life satisfaction. How we perceive ourselves is also important for our environment. Addiction disrupts the attitude towards ... -
Užívání alkoholu u studentů vysokých škol hlásících se k LGBTQ komunitě
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Background: Being non-heterosexual is still not fully accepted in the Czech Republic and research shows that the stressors that affect community members, negatively impact their mental health and therefore can among others ... -
Možnosti podpory funkční komunikace u pacientů s expresivní afázií ze strany ergoterapeuta
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Title: The Role of an Occupational Therapist in Supporting Functional Communication for People with Expressive Aphasia Abstract: The bachelor thesis is theoretical and practical. The aim of the bachelor thesis is to find ... -
Genetické faktory familiární hyperlipidemie a prevence kardiovaskulárních onemocnění
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 5. 9. 2023Familial hyperlipidemias are still a current cause of premature development of atherosclerotic cardiovascular disease (ASCVD). Heredity plays an important role in the development of these diseases. Genetic testing helps ... -
Integrovaná léčba osob s duální diagnózou v programu následné péče: série kazuistik
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Background: In the addiction treatment continuum, there is a relatively large group of clients with a dual diagnosis who repeatedly fail in treatment and follow-up treatment, with frequent relapses and recurrences of the ... -
Problémové užívání návykových látek mezi migranty arabského původu v české republice
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023Background: In recent years, a constant number of people from other countries have moved to the Czech Republic, who, unlike in the 1990s, no longer continue west, but increasingly want to settle permanently in the Czech ... -
Roztroušená skleróza - klinické a paraklinické markery pro sledování aktivity nemoci a faktory ovlivňující její průběh
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 11. 9. 2023Multiple sclerosis (MS) is a chronic neurological disease that, without treatment, leads over years to decades to severe disability in most patients. We cannot cure the disease, but there is growing evidence that early ... -
Rodinná terapie pro rodinné příslušníky adiktologických klientů
Defence status: DEFENDED(Univerzita Karlova, 1. lékařská fakulta, 2023)Date of defense: 14. 9. 2023
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