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Nucleolus and Its Associated Chromatin
Jadérko a jeho asociovaný chromatin
dissertation thesis (DEFENDED)
Advisor: Raška, Ivan
Date Issued: 2009
Date of defense: 29. 01. 2009
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: Savčí chromosomy zaujímají v jádře buňky tzv. chromosomální teritoria, jejichž umístění je v rámci buněčného jádra nenáhodné. Kontroverzním problémem však zůstává, zda je uspořádání chromosomálních teritorií (respektive ...
Mammalian chromosomes occupy chromosome territories within nuclear space the positions of which are generally accepted as non-random. However, it is still controversial whether position of chromosome territories is maintained, ...
Mammalian chromosomes occupy chromosome territories within nuclear space the positions of which are generally accepted as non-random. However, it is still controversial whether position of chromosome territories is maintained, ...
Relationship between Large-scale Chromatin Organization and Nucleolus in Human Cells
název v českém jazyce není uveden
dissertation thesis (DEFENDED)
Advisor: Raška, Ivan
Date Issued: 2008
Date of defense: 12. 06. 2008
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: In human cells ribosomal genes are organized as clusters called Nucleolus Organizer Regions (NORs) that are situated on the short arms of acrocentric chromosomes. It was found that essential components of the RNA polymerase ...
Orphan Nuclear Receptor TLX (NR2E1) in Regulation of Cell Reproduction and Differentiation
Sirotčí jaderný receptor TLX (NR2E1) v regulaci buněčné reprodukce a diferenciace
dissertation thesis (DEFENDED)
Advisor: Kostrouch, Zdeněk
Date Issued: 2012
Date of defense: 27. 09. 2012
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: Jaderné receptory zahrnují rozsáhlou rodinu transkripčních faktorů, které jsou silnými regulátory tkáňového metabolismu, homeostázy a vývoje tkáně živočišných druhů včetně člověka. Jsou zvláště zajímavé pro svoji schopnost ...
Nuclear receptors constitute a large family of transcription factors that are powerful regulators of animal tissue metabolism, homeostasis, tissue maintenance and development. They are particularly attractive for their ...
Nuclear receptors constitute a large family of transcription factors that are powerful regulators of animal tissue metabolism, homeostasis, tissue maintenance and development. They are particularly attractive for their ...
Thyroid hormone receptors and selected interacting proteins in glial tumors: The analysis of the expression and regulatory potential
Receptory tyroidního hormonu a vybrané interagující proteiny v gliálních nádorech: Analýza exprese a regulačního potenciálu
dissertation thesis (DEFENDED)
Advisor: Kostrouch, Zdeněk
Date Issued: 2007
Date of defense: 07. 06. 2007
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract not found
Assembly and recycling of functional splicing in vivo
Formování a recyklace funkčních sestřihových komplexů in vivo
dissertation thesis (DEFENDED)
Advisor: Staněk, David
Date Issued: 2010
Date of defense: 09. 09. 2010
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract not found
The role of evolutionarily conserved proteins BIR-1/Survivin and SKP-1 in the regulation of gene expression
Úloha evolučně konzervovaných proteinů BIR-1/Survivin a SKP-1 v regulaci genové exprese
dissertation thesis (DEFENDED)
Advisor: Kostrouch, Zdeněk
Date Issued: 2016
Date of defense: 29. 11. 2016
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: Souhrn SKIP a BIR/Survivin jsou evolučně zachovalé proteiny. SKIP je známý transkripční a sestřihový kofaktor a BIR-1/Survivin reguluje bunečné dělení, genovou expresi a vývoj. Inaktivace SKP-1 a BIR-1 indukuje podobné ...
SKIP and BIR/Survivin are evolutionarily conserved proteins. SKIP is a known transcription and splicing cofactor while BIR-1/Survivin regulates cell division, gene expression and development. Loss of function of C. elegans ...
SKIP and BIR/Survivin are evolutionarily conserved proteins. SKIP is a known transcription and splicing cofactor while BIR-1/Survivin regulates cell division, gene expression and development. Loss of function of C. elegans ...
Computational methods in single molecule localization microscopy
Výpočetní metody v jednomolekulové lokalizační mikroskopii
dissertation thesis (DEFENDED)
Advisor: Hagen, Guy Michael
Date Issued: 2016
Date of defense: 05. 12. 2016
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: Výpočetní metody v jednomolekulové lokalizační mikroskopii Abstrakt Fluorescenční mikroskopie je jedním z hlavních nástrojů biomedicínského výzkumu díky tomu, že se jedná o neinvazivní nedestruktivní a vysoce specifickou ...
Computational methods in single molecule localization microscopy Abstract Fluorescence microscopy is one of the chief tools used in biomedical research as it is a non invasive, non destructive, and highly specific imaging ...
Computational methods in single molecule localization microscopy Abstract Fluorescence microscopy is one of the chief tools used in biomedical research as it is a non invasive, non destructive, and highly specific imaging ...
The relationship between higher order chromain structure and gene silencing
Vztah vyšších chromatinových struktur a genové umlčování
dissertation thesis (DEFENDED)
Advisor: Cmarko, Dušan
Date Issued: 2012
Date of defense: 20. 09. 2012
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract not found
Image analysis of fluorescently labeled nuclear structures: DNA replication in focus
název v českém jazyce není uveden
dissertation thesis (DEFENDED)
Advisor: Raška, Ivan
Date Issued: 2006
Date of defense: 02. 02. 2006
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: In this thesis, we expanded the knowledge about some aspects of DNA replication in human cell nucleus with the help of microscopic techniques and advanced mathematical approaches. DNA replication was studied from several ...
Study of the mechanism of gene expression regulation at the level of functional organization of chromatin domains.
Studium mechanizmu regulace genové exprese na úrovni funkční organizace chromatinových domén.
dissertation thesis (DEFENDED)
Advisor: Cmarko, Dušan
Date Issued: 2018
Date of defense: 15. 11. 2018
Faculty / Institute: 1. lékařská fakulta / First Faculty of Medicine
Abstract: - 1 - ABSTRAKT Jadérka (nucleoli) se vytvářejí na základě aktivity genů ribozomální DNA (rDNA), nazývaných Nucleolus Organizer Regions (NOR). Základní komponenty jadérek, fibrilární centra (FC) a denzní fibrilární komponenty ...
- 1 - ABSTRACT Nucleoli are formed on the basis of genes of ribosomal DNA (rDNA) clusters called Nucleolus Organizer Regions (NORs). The essential structural components of the nucleoli, Fibrillar Centers (FC) and Dense ...
- 1 - ABSTRACT Nucleoli are formed on the basis of genes of ribosomal DNA (rDNA) clusters called Nucleolus Organizer Regions (NORs). The essential structural components of the nucleoli, Fibrillar Centers (FC) and Dense ...