Browsing by Author "Hrabánková, Klára"
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Use of polymer prodrugs containing cucurbitacin D for the treatment of experimental tumors
Defence status: DEFENDEDHrabánková, Klára (Univerzita Karlova, Přírodovědecká fakulta, 2021)Date of defense: 1. 6. 2021Chemotherapy is still the most widely used anti-cancer treatment. The majority of chemotherapeutics inhibit proliferating cells generally, not selectively cancer cells. The side effects associated with chemotherapy can be ... -
Úloha indolamin 2,3-dioxygenázy v progresi nádorů a její ovlivnění při terapii
Defence status: DEFENDEDHrabánková, Klára (Univerzita Karlova, Přírodovědecká fakulta, 2018)Date of defense: 4. 6. 2018Indoleamine 2,3-dioxygenase (IDO) is an enzyme that is physiologically expressed in many tissues including small intestine, lung, female genital tract and placenta. It is a key enzyme in metabolism of tryptophan and catalyses ...