Browsing by Advisor "Vožeh, František"
Now showing items 1-6 of 6
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Cognitive and emotional abnormalities in cerebellar mutant mice
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2016)Date of defense: 23. 3. 20163 SUMMARY Hereditary cerebellar ataxias represent a heterogeneous group of neurodegenerative disorders. Variability of human hereditary ataxias is also reflected in animal models of cerebellar disorders. The most frequently ... -
Experimentální studie mechanismů neurodegenerace za různých podmínek
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2019)Date of defense: 11. 4. 2019EXPERIMENTAL STUDY OF MECHANISMS OF NEURODEGENERATION IN DIFFERENT CONDITIONS - SUMMARY MUDr. Zdeňka Purkartová The cerebellum is an important structure involved in motor coordination and many other functions including ... -
Motorické a kognitivní důsledky vrozené mozečkové degenerace a některé možnosti jeího ovlivnění
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2006)Date of defense: 13. 4. 2006The motor and cognitive consequences of inborn cerebellar degeneration and some possibilities how to influence it The cerebellum is traditionally considered to be a coordinator of movements and equilibrium and a regulator ... -
Možnosti a význam dlouhodobé kultivace embryonálních buněk různých živočišných druhů
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2012)Date of defense: 15. 3. 2012Embryonic cells inside the blastocyst, which divide and differentiate into cells of all tissues of organism, are called embryonic stem (ES) cells. Using the ES cells for transplantations is one the potential ways in ... -
Role hmatových vousů v kompenzaci zrakového deficitu a vliv neurodegenerativního postižení na krosmodální plasticitu u myšího modelu retinální a olivocerebelární degenerace
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2015)Date of defense: 23. 4. 2015Sensory deprivation in one modality can enhance the development of the remaining modalities via mechanisms of synaptic plasticity. Mice of C3H strain suffers from RD1 retinal degeneration that leads to visual impairment ... -
Vliv transplantace tkáně mozečku a fyzické aktivity na schopnost prostorové orientace u mutantních myší typu Lurcher
Defence status: DEFENDED(Univerzita Karlova, Lékařská fakulta v Plzni, 2008)Date of defense: 23. 6. 2008Lurcher mutant mice represent a model of olivocerebellar degeneration. They are heterozygots carrying a mutation in the glutamate receptor 52-subunit gene. The receptor malfunction causes excitotoxic apoptosis of Purkinje ...